Dr. Usmani has carried out extensive research in his area of expertise, Islamic finance, and his book, A Guide to Islamic Banking, is well known and regarded as a manual of Islamic Banking. In addition to his position on the Shariah Supervisory Board of Guidance Financial Group, he is a Shariah advisor or Shariah supervisory board member to several institutions, including State Bank of Pakistan, Meezan Bank, UBS, Credit Suisse, HSBC Amanah and Lloyds T.S.B. Dr. Usmani conducts training sessions and lectures in Jamia Darul Uloom, Karachi and the Institute of Business Administration, Karachi (IBA). He holds an M.A. and a Ph.D. in Islamic Finance and M.A. (Arabic and Islamic Studies) as well as Alimiyyah and Takhassus degrees, with a specialization in Islamic Jurisprudence, from Jamia Darul Uloom, Karachi.

